Kanski The young adult endothelial density is 3000 cells per mm^2 Corneal oedema develops at about a density of 500 cells/mm

folds in descemet membrane are also known as striate keratopathy

There is a difference between epithelial oedema and stromal oedema and descemet membrane folds

specular microscopy looks at the corneal density - Corneal oedema is unlikely at a density above 1000 cells per mm2

Epithelial oedema is marked by microcysts and bullae (bullous keratopathy) of the cornea Rupture of the bullae is associated with marked pain This can cause subepithelial scaring and peripheral vascularisation

It seems that: - Microcystic changes of the epithelium +/- bullae - Stromal thickness and haze - DMFs