Sarcoidosis as a medical disease
There’s a good NEJM review I think, try and read that
Diagnosis: histological confirmation
- If there is necrosis in the centre, we call it caseous
- If there is no necrosis, it is non caseating
Open Evidence
Gold standard
elevated serum ACE
Sarcoidosis as a ophthalmic disease
Exam features
mutton fat like keratic precipitates
iris nodules
You get granulomas in the uveal tract!!
Treatment
Treatable entities
anterior and intermediate uveitis is treated with stepwise fashion as per idiopathic
posterior uveitis requires systemic steroids +/- immunosuppressants
Peripheral retinal neo vascularisation can be treated with PRP
CMO may respond to NSAID
Glaucoma (nodules in angle)
Cataract
gtt PF
PO Pred
Adalimumab
occ Hycor